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Pharmacelsus Assays und Publikationen

Publikationen

Download Optimized Human Hepatic in vitro ModelsOptimized Human Hepatic in vitro Models (PHA_Optimized_Human_Hepatic_in_vitro_models.pdf)
 Veröffentlichung zum Thema ""

Discovery Lead Optimization Services

Download Determination of Aqueous SolubilityDetermination of Aqueous Solubility (PHA_Solubility_assay_01.pdf)
Download Determination of the pKa-valueDetermination of the pKa-value (PHA_pKa_assay_01.pdf)
Download Determination of logP and logDDetermination of logP and logD (PHA_logP_logD_assay_01.pdf)
Download Lipophilicity Determination by Chromatographic Hydrophobicity IndexLipophilicity Determination by Chromatographic Hydrophobicity Index (PHA_LogP_assay_01.pdf)
Download Determination of Chemical StabilityDetermination of Chemical Stability (PHA_Chemstability_assay_01.pdf)
Download Metabolic Stability Determination in vitroMetabolic Stability Determination in vitro (PHA_Hepatocytes_assay_01.pdf)
 Hepatocytes (human, rat)
Download Metabolic Stability Determination in vitroMetabolic Stability Determination in vitro (PHA_Microsomes_assay_01.pdf)
 Microsomes (human, monkey, dog, rat, mouse)
Download Metabolite Detection and Characterization (liver microsomes, hepatocytes)Metabolite Detection and Characterization (liver microsomes, hepatocytes) (PHA_Metabolite_ID_01.pdf)
Download CYP450 ProfilingCYP450 Profiling (PHA_CYP450_profiling_01.pdf)
Download Drug InteractionDrug Interaction (PHA_CYP-Inhibition_assay_01.pdf)
Download Plasma StabilityPlasma Stability (PHA_Plasmastability_assay_01.pdf)
Download Plasma Protein BindingPlasma Protein Binding (PHA_ProtBind_assay_01.pdf)
Download Single in vitro CytotoxicitySingle in vitro Cytotoxicity (PHA_Cytotox_assay_01.pdf)

Pharmacokinetic

Download Permeability Test Sequence: SUCCELERATORPermeability Test Sequence: SUCCELERATOR (PHA_Succelerator_2005_01.pdf)
 Kurzversion
Download Cassette DosingCassette Dosing (PHA_Cassette_dosing_01.pdf)
Download Single in vivo PKSingle in vivo PK (PHA_Pharmacokinetics_assay_01.pdf)
Download PK / PD RelationshipPK / PD Relationship (PHA_PK_PD_relation_01.pdf)

Target Based Bioassays

Download Aromatase Inhibitors - In vitroAromatase Inhibitors - In vitro (PHA_Aromatase_in_vitro_01.pdf)
Download Aromatase Inhibitors - In vivoAromatase Inhibitors - In vivo (PHA_Aromatase_in_vivo_assay_01.pdf)
Download Aromatase Test SequenceAromatase Test Sequence (PHA_Arotestsystem_II_01.pdf)
Download 5-alpha-Reductase Inhibitors - In vivo5-alpha-Reductase Inhibitors - In vivo (PHA_Reductase_in_vivo_assay_01.pdf)
Download LHRH Agonists/Antagonists - In vitroLHRH Agonists/Antagonists - In vitro (PHA_LHRH_Antagonists_in_vitro_assay_01.pdf)
Download LHRH Test SequenceLHRH Test Sequence (PHA_Agonists-Antagonists-Testsequence_01.pdf)

Neurodegenerative Diseases

Allergic and Antiallergic Action

Download Allergic and Anti-Allergic PotencyAllergic and Anti-Allergic Potency (PHA_Allergic_antiallergic_potency_01.pdf)

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   Messekalender/Termine:
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19.11.08:
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